Podcast Episode 1
About
Curated, evidence-led educational resources and formats designed for busy clinicians.
Indications
Hypertension • Coronary heart disease (angina pectoris) • Stable chronic heart failure
Once daily
Simple, practical dosing approach designed for routine clinical use.
Administration
Morning dosing • With or without food • Swallow with liquid • Do not chew
Major Landmark trials of Bisoprolol were performed with Concor® / Concor® COR
- CIBIS II (Concor® COR)*
- TIBBS, CREATIVE (Concor®)*
Clinical evidence
Expandable evidence blocks for outcomes, 24-hour control, and practical endpoints (populate with brand-approved references).
Long-term cardioprotection outcomes
- Position: evidence-led use across cardiovascular indications where β-blockade is appropriate.
- Insert: trial names, endpoints, and citations approved for the brand.
24-hour heart rate and blood pressure control
- Highlight once-daily dosing and clinical monitoring in appropriate patients.
- Insert: ABPM or HR control datasets if approved.
Dosing and titration
Hypertension or angina pectoris
- Usual initial dose: 5 mg once daily
- If necessary, increase to 10 mg once daily
- Maximum recommended dose: 20 mg once daily
Stable chronic heart failure
- Start: 1.25 mg once daily
- Stepwise increase to 2.5 mg, 3.75 mg, 5 mg, 7.5 mg, 10 mg once daily
- Intervals: two weeks or longer, as tolerated
Renal or hepatic impairment
- In severe renal impairment (creatinine clearance less than 20 ml per minute) or severe hepatic impairment, daily dose of 10 mg must not be exceeded