COFFEE CONSUMPTION MAY REDUCE SEVERITY OF NON-ALCOHOLIC FATTY LIVER DISEASE IN PEOPLE WITH TYPE 2 DIABETES; STUDY

A new study by the University of Coimbra, published in Nutrients, has revealed that caffeine, polyphenols, and other natural products found in coffee may help reduce the severity of Non-Alcoholic Fatty Liver Disease (NAFLD) among overweight people with type 2 diabetes

Study participants with higher coffee intake had healthier livers than others. Subjects with higher caffeine levels were less likely to have liver fibrosis, while higher levels of non-caffeine coffee components were significantly associated with reduced fatty liver index scores. The study suggests that for overweight T2D patients, a higher intake of coffee is associated with less severe NAFLD

Participants In The Study Who Drank More Coffee Had Healthier Livers. Higher Levels Of Non-Caffeinated Coffee Components Were Substantially Correlated With Lower Levels Of Fatty Liver Index Scores, But Subjects With Higher Caffeine Levels Were Less Likely To Have Liver Fibrosis.

156 Middle-Aged Borderline Obese Volunteers Were Polled About Their Coffee Use, 98 Of Whom Had T2D And Gave 24-Hour Urine Samples. This Was Used To Measure The Natural Byproducts Of The Body Breaking Down Coffee, Including Caffeine And Non-Caffeine Metabolites. In Order To Obtain More Precise, Quantitative Information On Coffee Consumption, A Recent Shift Was Made Toward Analysing Urine Rather Than Self-Reported Consumption.

In NAFLD And Other Chronic Liver Diseases, Caffeine Consumption Is Linked To A Reduction In Liver Fibrosis. . Other Coffee Ingredients, Such As Polyphenols, May Lessen Oxidative Stress In The Liver, Which Lowers The Incidence Of Fibrosis And Enhances Glucose Homeostasis In Both Healthy And Overweight Subjects. All Of These Elements Might Also Lessen How Severe T2D Is

"Due To Changes In Modern Diet And Lifestyle, There Is An Increase In Obesity Rates And Incidence Of Both T2D And NAFLD, Which Can Ultimately Develop Into More Severe And Irreversible Conditions, Burdening Healthcare Systems," Said John Griffith Jones, Ph.D., The Study's Corresponding Author And Senior Researcher At The Center For Neuroscience And Cell Biology At The University Of Coimbra In Portugal.

This research study is published in Nutrients, titled: ‘Increased intake of both caffeine and non-caffeine coffee components is associated with reduced NAFLD severity in subjects with type 2 diabetes.’ It was sponsored by the Institute for Scientific Information on Coffee (ISIC).