KNOW HOW SEVERE PSORIASIS IS LINKED WITH INCREASED RISK OF HEART DISEASE

Around 125 million people worldwide (two to three percent of the world's population) have psoriasis, an inflammatory disease that causes a rash with itchy, scaly patches that most frequently appear on the knees, elbows, trunk, and scalp. When the condition is severe, the skin around the joints may split and bleed.

The body of the patient believes that its own tissues are foreign intruders that need to be destroyed. It is typically an incurable, lifelong sickness that runs in families and cannot be treated with an over-the-counter skin remedy, unlike a simple rash. It does not transmit to other people.

Stress, tobacco use, excessive alcohol use, strep throat infections, cold and dry weather, terrible sunburns, and some drugs including lithium, prednisone, and hydroxychloroquine can all cause attacks.

As if dealing with this were not difficult enough, a study from the University of Padova in Italy that was just published in the Journal of Investigative Dermatology discovered that people with severe psoriasis have a higher chance of developing heart disease and a reduced coronary flow.

The study was named "Coronary microvascular dysfunction in asymptomatic patients with severe psoriasis." The symptoms of the illness can be improved by maintaining overall health as well as by using a specific cream or moisturizer or using specific drugs.

How does this affect the heart? In the new investigation, coronary microcirculation was assessed using transthoracic Doppler echocardiography on 503 psoriasis patients who did not have clinical cardiovascular disease. In the study population, 31.5% of asymptomatic patients had a high incidence of coronary microvascular dysfunction, according to researchers.

The researchers said that they intended to further explore the incidence of coronary microvascular dysfunction, as measured by coronary flow reserve (CFR), and its relationships with the severity and duration of psoriasis as well as other patient features in a large cohort of patients with severe psoriasis.

Angio-CT was performed on individuals with a reduced CFR to rule out coronary artery stenosis, although none of the patients had coronary artery disease. As a result, coronary microvascular dysfunction was seen in all of the individuals in our sample with impaired CFR, Researchers said.

The study's findings demonstrated that traditional cardiovascular risk factors such as hyperlipidemia, smoking, and Type 2 diabetes were not independently related to decreased CFR in patients with severe psoriasis.

These findings highlight the significance of taking inflammation and psoriasis-related factors into account when determining the cardiovascular risk in individuals with severe psoriasis.

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