UK STUDY LINKS ULTRA-PROCESSED FOODS TO HEIGHTENED CANCER RISK

Ultra-processed foods are frequently readily available, reasonably priced, and widely advertised often as healthy options. However, these foods generally contain more salt, fat, sugar, and artificial additives. They are now well understood to be linked with a number of negative health outcomes, such as obesity, type 2 diabetes, and cardiovascular disease.

Higher consumption of ultra-processed foods may be linked to an increased risk of developing and dying from cancer, an Imperial College London-led observational study suggests.

Researchers from Imperial’s School of Public Health have produced the most comprehensive assessment to date of the association between ultra-processed foods and the risk of developing cancers. Ultra-processed foods are food items that have been heavily processed during their production, such as fizzy drinks, mass-produced packaged bread, many ready meals, and most breakfast cereals.

The first UK study of its kind used UK Biobank records to collect information on the diets of 200,000 middle-aged adult participants. Researchers monitored participants’ health over a 10-year period, looking at the risk of developing any cancer overall as well as the specific risk of developing 34 types of cancer. They also looked at the risk of people dying from cancer.

The study found that higher consumption of ultra-processed foods was associated with a greater risk of developing cancer overall, specifically ovarian and brain cancers. It was also associated with an increased risk of dying from cancer, most notably ovarian and breast cancers.

For every 10 percent increase in ultra-processed food in a person’s diet, there was an increased incidence of 2 percent for cancer overall and a 19 percent increase for ovarian cancer specifically. Each 10 percent increase in ultra-processed food consumption was also associated with increased mortality for cancer overall by 6 percent, alongside a 16 percent increase for breast cancer and a 30 percent increase for ovarian cancer. These links remained after adjusting for a range of socio-economic, behavioral, and dietary factors, such as smoking status, physical activity, and body mass index (BMI).

The Imperial team carried out the study, which is published in eClinicalMedicine, in collaboration with researchers from the International Agency for Research on Cancer (IARC), the University of São Paulo, and NOVA University Lisbon.

Dr. Eszter Vamos, lead senior author for the study, from Imperial College London’s School of Public Health, said: “This study adds to the growing evidence that ultra-processed foods are likely to negatively impact our health including our risk for cancer. Given the high levels of consumption in UK adults and children, this has important implications for future health outcomes.

“Although our study cannot prove causation, other available evidence shows that reducing ultra-processed foods in our diet could provide important health benefits. Further research is needed to confirm these findings and understand the best public health strategies to reduce the widespread presence and harms of ultra-processed foods in our diet.”

Dr. Kiara Chang, the first author of the study, from Imperial College London’s School of Public Health, said: “The average person in the UK consumes more than half of their daily energy intake from ultra-processed foods. This is exceptionally high and concerning as ultra-processed foods are produced with industrially derived ingredients and often use food additives to adjust color, flavor, consistency, texture, or extend shelf life.

Dr. Chang added: “We need clear front-of-pack warning labels for ultra-processed foods to aid consumer choices, and our sugar tax should be extended to cover ultra-processed fizzy drinks, fruit-based and milk-based drinks, as well as other ultra-processed products. She says “Lower-income households are particularly vulnerable to these cheap and unhealthy ultra-processed foods. Minimally processed and freshly prepared meals should be subsidized to ensure everyone has access to healthy, nutritious, and affordable options.”

The researchers note that their study is observational, so does not show a causal link between ultra-processed foods and cancer due to the observational nature of the research. More work is needed in this area to establish a causal link.

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