Intraoperative autologous transfusion for scoliosis surgery a reliable option
Adolescent idiopathic scoliosis (AIS) is a common spinal deformity, and posterior instrumentation and fusion is a common method for treating AIS. However, the operation is complicated and causes massive intraoperative blood loss upto 650–2,839 mL. Intraoperative autologous transfusion (IAT) is in practice for scoliosis surgery for decades; however, its cost-effectiveness remains debatable.
BMC Anesthesiology reports a review that estimated the cost-effectiveness and blood loss in Intraoperative autologous transfusion (IAT) was effective as it was related to the volume of blood loss, and when the blood loss volume was less than 1,500 mL, IAT was cost-effective, drastically reducing the demand for allogeneic RBC and total RBC transfusion cost.
The researchers reviewed medical records of 402 patients who underwent AIS surgery. The patients were divided into different groups according to the intraoperative blood loss volume (group A: ≥500 to < 1000 mL, B: ≥1,000 to < 1,500 mL, and C: ≥1,500 mL) and whether IAT was used (i.e., IAT and no-IAT groups). The volume of blood loss, volume of transfused allogeneic red blood cells (RBC), and RBC transfusion costs were analysed. Univariate and multivariate logistic regression analyses were used to identify the independent risk factors of massive intraoperative blood loss (≥ 1,000 mL and ≥ 1,500 mL). A receiver operating characteristic (ROC) curve was used to analyse the cut-off values of the factors contributing to massive intraoperative blood loss.
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