Liposomal Bupivacaine may not reduce pain after abdominal wall reconstruction surgery
Multiple pain control strategies that do not rely on opioids have been developed in recent years, especially for postoperative pain. The most commonly used anaesthesia to replace opioid is simple bupivacaine.
In a recent study, researchers reported that in patients undergoing abdominal wall reconstruction, liposomal bupivacaine transversus abdominus plane block did not reduce the postoperative opioid use when compared with simple bupivacaine and a placebo. The research has been published in the journal Annals of Surgery on December 02, 2020.
Overuse of opiates in surgical patients has been associated with dependence and poor patient outcomes. Ultrasound-guided transverse abdominal plane (TAP) blocks provide a means for administering non-narcotic pain control in patients undergoing abdominal surgery. Despite the widespread use of liposomal bupivacaine in transversus abdominis plane block, there is inadequate evidence demonstrating its efficacy in open abdominal wall reconstruction. Therefore, researchers of the Cleveland, Ohio, conducted a study to evaluate the efficacy of liposomal bupivacaine on postoperative opioid requirement and pain following abdominal wall reconstruction.
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