LMA not superior to face-mask ventilation for lowering death risk in neonatal asphyxia: NEJM
Written By : MD Bureau
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2020-11-27 09:30 GMT | Update On 2020-11-27 09:30 GMT
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Researchers have found in a new study that laryngeal Mask Airway is not as effective as face-mask ventilation in lowering early neonatal death and moderate-to-severe hypoxic–ischemic encephalopathy. The study has been published in The New England journal of Medicine on 26, November 2020.
Face-mask ventilation is the most common resuscitation method for birth asphyxia. Ventilation with a cuffless laryngeal mask airway (LMA) has potential advantages over face-mask ventilation during neonatal resuscitation in low-income countries, but whether the use of an LMA reduces mortality and morbidity among neonates with asphyxia is unknown.
Birth asphyxia is the third leading cause of neonatal death, accounting for approximately 700,000 deaths each year. Effective positive-pressure ventilation is the most vital step in neonatal resuscitation. However, delivering proper tidal volumes with a face mask is difficult due to Mask leakage, airway blockage, and poor chest expansion. International guidelines have suggested the use of the laryngeal mask airway (LMA) in cases of failure of positive-pressure ventilation with the use of a face mask during resuscitation of neonates or if intubation is unsuccessful or not feasible. The effectiveness and safety of the LMA as compared with the face mask have been identified as important knowledge gaps. So the researchers conducted a Neonatal Supraglottic Airway (NeoSupra) trial to compare the use of uncuffed LMA (Laryngeal Mask Airway) vs. FMV ( Face MAsk Ventilation) during neonatal resuscitation.
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