Perfusion index may help assess analgesia during laparoscopic surgeries under general anaesthesia
Perfusion index may help assess analgesia during laparoscopic surgeries under general anaesthesia, according to a new study published in Indian Journal of Anaesthesia.
Anaesthesia is a combination of analgesia, unconsciousness, and paralysis of muscles. Because quantifying nociception under anaesthesia is difficult, the response to nociception is utilised to monitor it by increasing sympathetic activity or decreasing parasympathetic stimulation (i.e., increased heart rate (HR)).
The perfusion index (PI) is a continuous and non-invasive measure of peripheral perfusion. Sympathetic tone variations impact smooth muscle tone and may alter perfusion, although they are unaffected by saturation or HR variability.
A recent research looked at the changes in perfusion index (PI) in response to unpleasant stimuli when under general anaesthetic.
Twenty patients between the ages of 20 and 45, with informed consent, who were undergoing an elective laparoscopic procedure and were classified as physical status class I by the American Society of Anesthesiologists (ASA), were connected to standard monitors and SEDLINE, pulse oximetry (Root, Masimo Corporation®, Irvine, CA, USA) to monitor PI and Pleth-Variability Index (PVi). Anaesthesia was given to the patient. Pre-induction, during induction, before and after intubation, at the time of pneumoperitoneum (P0), and at the time of first laparoscopic port insertion, PI, PVi, heart rate (HR), and non-invasive blood pressure were all monitored (P1). After that, a 0.5 mcg/kg intravenous injection of fentanyl was given, and values were taken at the second (P2) and third (P3) port insertions. For up to 30 minutes, the aforementioned characteristics were recorded. Paired t tests were used to corroborate the findings statistically.
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