Addition of catheter ablation strategies improve efficacy of pulmonary vein isolation in AF
Sweden: The efficacy of pulmonary vein isolation (PVI) alone can be increased by combining it with additional catheter ablation (CA) strategies, such as autonomic modulation and additional lines, a recent study in BMC Medicine has suggested.
Also, no differences in safety were observed implying that these strategies could be considered in treating patients with atrial fibrillation (AF). The study provides decision-makers with comprehensive and comparative evidence about the safety and efficacy of different CA strategies.
There is no consensus on the most efficient strategy of catheter ablation for atrial fibrillation patients. Emmanouil Charitakis, Linköping University, Linköping, Sweden, and colleagues aimed to compare the safety and efficacy of different CA strategies for AF ablation through network meta-analysis (NMA).
For this purpose, the researchers conducted a systematic search of online databases up to October 5th, 2020. It included randomized controlled trials (RCT) comparing different CA approaches. Efficacy was defined as recurrence of arrhythmia after CA and safety as any reported complication related to the procedure during a minimum follow-up time of 6 months.
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