Stress Cardiac MRI, a reliable method to assess prognosis in CAD patients: JACC

The researchers found that out of 755 patients (age 64 ± 11 years, 64% male), and they observed 97 MI/CV deaths and 210 MACE over a median follow-up of 5.3 years. Presence of ischemia demonstrated a significant association with MI/CV death (HR: 2.30) and MACE (HR: 2.24). In a multivariate model that was adjusted for CV risk factors, it was observed that ischemia maintained strong association with MI/CV death (HR: 1.84) and MACE (HR: 1.77) and reclassified 95% of patients at intermediate pretest risk (62% to low risk, 33% to high risk) with corresponding changes in the observed event rates of 1.4% and 5.3% per year for low and high post-test risk, respectively.

The researchers concluded that "In a multicenter cohort of patients with known CAD, CMR-assessed ischemia was strongly associated with MI/CV death and reclassified patient risk beyond CV risk factors, especially in those considered to be at intermediate risk. Absence of ischemia was associated with a <2% annual rate of MI/CV death (Stress CMR Perfusion Imaging in the United States [SPINS] Study."

For further information:

Panagiotis Antiochos, Yin Ge, Bobak Heydari, Kevin Steel, Scott Bingham, Shuaib M. Abdullah, J. Ronald Mikolich, Andrew E. Arai, W. Patricia Bandettini, Amit R. Patel, Afshin Farzaneh-Far, John F. Heitner, Chetan Shenoy, Steve W. Leung et al "Prognostic Value of Stress Cardiac Magnetic Resonance in Patients With Known Coronary Artery Disease" Journal American College Cardiology Img. Aug 17, 2021DOI: 10.1016/j.jcmg.2021.06.025.