CKD tied to higher prevalence of incomplete revascularization in Chronic coronary syndrome patients, reveals Indian Study

Repeated revascularization (P < 0.001), STEMI (P = 0.003), stent thrombosis (P = 0.015), MACE (P < 0.001), stroke (P < 0.001), and all-cause mortality (P < 0.001) were more prevalent among patients with incomplete revascularization. Multivariate regression analysis revealed eGFR (P = 0.001) and Syntax score (SS) (P=<0.001) as independent predictors of incomplete revascularization. The optimal eGFR cutoff value for predicting partial revascularization is 49.50mL/min/1.73m2, with 58.8% sensitivity and 69.3 % specificity. Chronic kidney disease is associated with a higher syntax score and incomplete revascularization prevalence in CCS patients. Additionally, incomplete revascularization is associated with an increased incidence of major adverse cardiac events. In patients with CCS, CKD predicts partial revascularization and subsequent MACE.

Reference:

Shereen Ibrahim Farag, Shaimaa Ahmed Mostafa, Hamza Kabil, Mohamed Reda Elfaramawy. Chronic kidney disease's impact on revascularization and subsequent major adverse cardiovascular events in patients with chronic coronary syndrome, Indian Heart Journal. Volume 76, Issue 1, 2024, Pages 22-26, ISSN 0019-4832, https://doi.org/10.1016/j.ihj.2023.11.006. (https://www.sciencedirect.com/science/article/pii/S001948322300192X)