CMR-Derived ECV Predicts Long-Term Risk of MACE in 'True' MINOCA Patients: Study
China: Cardiac MRI-derived extracellular volume (ECV) levels vary based on the underlying cause of myocardial infarction with non-obstructive coronary arteries (MINOCA), with significantly higher ECV observed in patients with "true" MINOCA. Researchers have found in a new study that elevated ECV levels are independently associated with a higher risk of major adverse cardiovascular events (MACE) in this subgroup.
The study, led by Lei Chen and colleagues from the Department of Cardiology at Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China, was published in the International Journal of Cardiology. The findings provide important insights into the prognostic role of ECV in MINOCA and offer new opportunities to improve risk stratification and management of these patients.
MINOCA represents a complex clinical entity often leading to diagnostic uncertainty and undertreatment. Patients with this condition face considerable risks of adverse outcomes, including mortality and reduced quality of life, underscoring the need for improved diagnostic and prognostic strategies. While cardiac magnetic resonance (CMR) imaging is endorsed by both the American Heart Association (AHA) and the European Society of Cardiology (ESC) guidelines as a key tool in MINOCA evaluation, the role of CMR-derived ECV in predicting outcomes has remained poorly defined.
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