CPAP adherence lowers long term high BP among Sleep apnea patients after ACS

Key findings of the study:

• BP changes were comparable across the OSA and non-OSA groups after a median [25th;75th percentile] follow-up of 41.2 [18.3;59.6] months.
• AHI(>40 events/h) was associated with an increase in blood pressure, with a maximal difference in mean blood pressure of +3.3 mmHg at 30 months.
• After 18 months, mean BP was lower in OSA patients with good CPAP adherence (4 hours/night) than in non-OSA and patients with poor CPAP adherence, with a maximum mean difference (95% CI) of -4.7 (-6.7,-2.7) mmHg.
• A highest mean difference of -7.1 (-10.3,-3.8) mmHg was observed in patients with severe OSA.

ACS patients, with severe OSA is associated to a long-term elevation in blood pressure, which is decreased by good CPAP adherence, according to the authors' findings.

REFERENCE

A Aldoma, M Manuel Sanchez-De-La-Torre, E Gracia-Lavedan, ID Benitez, A Zapater, G Torres, A Sanchez-De-La-Torre, J De Batlle, A Targa, O Minguez, L Pascual, A Cortijo, D Martinez, M Dalmases, F Barbe-Illa, Long-term effect of obstructive sleep apnea and CPAP treatment on blood pressure control in patients after acute coronary syndrome, European Journal of Preventive Cardiology, Volume 29, Issue Supplement_1, May 2022, zwac056.096, https://doi.org/10.1093/eurjpc/zwac056.096