Easy-to-use ECG algorithm can predict coronary occlusion site in STEMI patients: Study

The study led to the following findings:

• In the derivation cohort, the algorithm correctly predicted the IRA in 88% of cases and both the IRA and its occlusion level (proximal vs. mid-distal) in 71% of cases.
• When applied to the validation cohort, the algorithm resulted in 88% and 67% diagnostic accuracies, respectively.
• In a real-world comparative test, the algorithm performed significantly better than expert physicians in identifying the site of the culprit occlusion.

"The internal validation suggested that the algorithm is reliable and accurate, making it appropriate for clinical practice," the researchers wrote in their conclusion. "This ECG algorithm can predict the culprit occlusion site in all STEMI patients and may be useful for determining prognosis and management guide of these patients."

Reference:

Gaspardone C, Romagnolo D, Fasolino A, Falasconi G, Beneduce A, Fiore G, Didelon E, Fortunato F, Galdieri C, Posteraro GA, Ingallina G, Ancona F, Biondi F, Maio SD, Casiraghi A, Slavich M, Borio G, Savastano S, Leonardi S, Agricola E, Oppizzi M, Gaspardone A, Pappone C, Montorfano M. A comprehensive and easy-to-use ECG algorithm to predict the coronary occlusion site in ST-segment elevation myocardial infarction. Am Heart J. 2022 Oct 19:S0002-8703(22)00272-1. doi: 10.1016/j.ahj.2022.10.077. Epub ahead of print. PMID: 36272451.