Flecainide may help achieve sinus rhythm in young rheumatic AF patients undergoing MVR
A recent study found that oral flecainide, a medication used to treat certain heart rhythm disorders, could be a valuable option for patients who continue to experience atrial fibrillation (AF) after successful mitral valve replacement (MVR). The findings were published in Indian Heart Journal.
The study, which involved 25 patients with chronic rheumatic AF following MVR, revealed promising outcomes. The patients had an average age of 34.4 years and had been experiencing AF for an average of 3.6 years. Researchers administered oral flecainide to these patients to assess its effectiveness in converting and maintaining sinus rhythm (SR), which is the normal heart rhythm.
Results from the study showed that a single oral dose of flecainide successfully restored SR in 24% of patients, while 84% achieved SR after undergoing direct current cardioversion (DCC) at 24 hours. The maintenance of SR at the six-month mark was observed in 69.5% of patients who received a mean flecainide dose of 93.10 ± 9.40 mg. Importantly, the medication was well tolerated, and no significant adverse effects were noted in terms of heart rhythm parameters.
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