Garlic consumption improves lipid metabolism and reduces Cardiovascular risk

The key highlights of the study were:

Garlic provided statistically significant changes of C-RP (SMD = −0.59; 95% CI = −0.92 to −0.25; p = .0007), HDL (SMD = 0.18; 95% CI = −0.00 to 0.37; p = .05); apolipoprotein-A (SMD = 0.68; 95% CI = 0.24 1.13; p = .002), LDL (SMD = −0.27; 95% CI = −0.46 to −0.08; p = .004), homocysteine (SMD = −0.66; 95% CI = −1.04 to −0.28; p = .0007), IL-6 (SMD = −1.08; 95% CI = −2.17 to 0.01; p = .05), and CAC score (SMD = −1.61; 95% CI = −2.66 to −0.57; p = .003).

In subgroup analysis, they found the overall effect was significantly effective in reducing Total Cholesterol, LDL levels and improving HDL levels in patients with cardiovascular risk.

In conclusion, the Authors suggest that the findings provide strong and consistent evidence regarding the intake of garlic and its effect as reducing risk factors of cardiovascular disease. Garlic might be considered a safe natural therapy to nullify inflammation in CAD patients.

Source:

Gadidala, S. K., Johny, E., Thomas, C., Nadella, M., Undela, K., & Adela, R. (2023). Effect of garlic extract on markers of lipid metabolism and inflammation in coronary artery disease ( CAD ) patients: A systematic review and meta‐analysis. In Phytotherapy Research. Wiley. https://doi.org/10.1002/ptr.7729