Heart disease in young linked to Intrauterine exposure to diabetes: Study
Researchers have found in a new study that Heart disease in adults and teenagers may be linked to Intrauterine exposure to diabetes.
The new research has been published in CMAJ (Canadian Medical Association Journal).
The researchers examined this potential association in a population-based birth cohort followed up to age 35 years.
A study of young adults and teenagers in Manitoba, Canada, whose mothers had diabetes during their pregnancies found the offspring had a 50% to 200% higher risk of developing heart disease before age 35 than those who were not exposed in the womb.
"These observations support our hypothesis that cardiovascular disease morbidity in adolescence and early adulthood is related to exposure to maternal diabetes in utero," writes Dr. Jonathan McGavock, Children's Hospital Research Institute of Manitoba and Associate Professor at the University of Manitoba, Winnipeg, Manitoba, with coauthors.
Researchers looked at data on more than 290 000 children born to almost 190 000 mothers in Manitoba between 1979 and 2005. Of the total children, 2.8% were exposed to gestational diabetes and 1.1% to pre-existing type 2 diabetes. Exposure to both types of diabetes became more common during the study period, a trend seen elsewhere in the world.
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