Higher AMR Index Tied to Increased Mortality and Cardiovascular Events Post-TAVR: Study Finds
China: A new study highlights that angiographic microvascular resistance (AMR) is an independent predictor of adverse clinical outcomes following transcatheter aortic valve replacement (TAVR). It found that an AMR index above 250 independently predicted adverse outcomes after TAVR.
"Over 40 months, patients with AMR >250 experienced a 1.94-fold higher risk of major adverse cardiovascular events (HR: 1.94), reduced event-free survival, increased all-cause mortality, and a greater incidence of new-onset atrial fibrillation. These findings establish AMR as a significant marker for assessing long-term risks in TAVR patients," the researchers reported in the Journal of the American Heart Association.
The coronary microcirculatory resistance index is essential for predicting patient outcomes. Coronary angiography-based methods provide a simple and cost-effective way to assess microcirculatory function. Considering this, Hongliang Zhang, National Center for Cardiovascular Disease Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China, and colleagues explored the prognostic significance of a novel angiographic microvascular resistance (AMR) index in patients undergoing transcatheter aortic valve replacement.
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