Higher BMI associated with higher prevalence of thin-cap fibroatheroma in Younger T2D Patients with CAD
Written By : Aditi
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2023-12-20 17:00 GMT | Update On 2023-12-21 06:38 GMT
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Japan: Masahiro Katamine et and colleagues, in a recent study, said that higher BMI is linked to a higher prevalence of TCFA in younger type 2 diabetes (T2D) patients with a history of coronary artery disease (CAD), especially those who have HbA1c ≥7.0%.
This study was published in Nutrition Metabolism and Cardiovascular Diseases.
The relationship between BMI and coronary plaque characteristics in younger T2D patients with CAD is yet to be explored.
One hundred thirty-eight younger T2D patients (<65 yrs) with CAD underwent OCT (optical coherence tomography) imaging of the culprit lesion. Patients were divided into higher BMI (n=68) and lower BMI (n=70) groups according to the median BMI (25.9 kg/m2.
Key findings from this investigation are:
- The high BMI group had a higher prevalence of thin-cap fibroatheroma (TCFA) (35.3 vs. 17.1%) than the lower BMI group.
- The prevalence of TCFA was higher in patients with higher BMI compared to lower BMI among patients with haemoglobin A1c (HbA1c) ≥7.0% with an odds ratio of 5.40, although a significant difference was not observed among patients with HbA1c <7.0% with OR 0.89.
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