Highly calcified Suprarenal aortic atheroma associated with AKI after transcatheter aortic valve replacement

The study results could be summarised as follows:

• Researchers included 222 patients with a mean age of 83.3 ± 5.7 years. (TAVR patients).
• 42.8% were males.
• 67/222 patients constituting 30.2%, had AKI-TAVR.
• Patients developing AKI-TAVR had higher Absolute SR-AAB and %SR-AAB.
• Patients who developed AKI-TAVR had higher mid‑calcium and 1 K plaque. They had no difference in AV-CS (p = 0.691).
• There was an increased risk of AKI when the %SR-AAB is >15.0% and the %SR-calcified plaque is >7.0%.
• %SR-AAB [OR 1.12] and %SR-calcified plaque [OR 5.60] had associated with AKI-TAVR.

We identified %SR-AAB >15.0% and %SR-calcified plaque >7.0% as optimal thresholds for predicting increased risk of AKI-TAVR from 3-knots spline analyses.

The study highlighted the usefulness of 3-dimensional multislice computed tomography in pre-TAVR evaluation.

The researchers in this study found higher supra-renal aortic atheroma burden (SR-AAB) and calcified plaque in AKI patients.

Further reading:

Supra-renal aortic atheroma extent and composition predict acute kidney injury after transcatheter aortic valve replacement: A three-dimensional computed tomography study.

DOI:https://doi.org/10.1016/j.ijcard.2023.03.053