In hospital Mortality risk higher in MI patients having cardiac arrest than those with Cardiogenic Shock

Recent research found that in-hospital mortality of Acute Myocardial Infarction complicated with Cardiac arrest was higher than that complicated with cardiogenic shock. The study was published in the journal, "Heart and Vessels, 2022." 

Acute Myocardial Infarction (AMI) when complicated with cardiogenic shock (CS) shows high in-hospital mortality. Similarly, AMI when complicated with cardiac arrest (CA) also shows the highest in-hospital mortality. But there is limited research comparing in-hospital mortality directly between AMI complicated with CS and that complicated with CA. Hence researchers from Japan conducted a study to compare in-hospital outcomes between AMI complicated with CS and complicated with CA. 

A retrospective study was performed on 195 AMI patients complicated by CS or CA. Patients were divided into the CA group having 109 subjects and the CS group with 86 subjects. CA group was subdivided into CA with persistent CS having 83 patients and CA without persistent CS having 26 patients. One-third of the study population died during the index admission.

Results: 

• In-hospital death was more frequently observed in the CA group (45.0%) than in the CS group (20.9%).
• In-hospital mortality was highest in the CA with persistent CS group (68.7%), followed by the CS group (20.9%), and least in the CA without persistent CS group (11.5%).
• Favorable neurological function was more frequently observed in the CA without persistent CS group (76.9%) and the CS group (74.4%) than in the CA with persistent CS group (27.7%). 

Thus, the researchers concluded that in-hospital mortality was higher in AMI patients with CA than in those with CS. They also observed the in-hospital mortality when AMI patients with CA were divided into those with and without persistent CS. They mentioned that in-hospital mortality was lowest in CA without persistent CS, followed by CS, and highest in CA with persistent CS. 

For the full article, click here: https://doi.org/10.1007/s00380-022-02145-5

Kasahara, T., Sakakura, K., Hori, N. et al. Comparison of in-hospital outcomes of acute myocardial infarction between patients with cardiogenic shock and with cardiac arrest. Heart Vessels (2022).