Increased mortality and complication rates observed in women following TAVR, suggests study

A new study published in the International Journal of Cardiology showed that regardless of sex, there are still prominent differences in Transcatheter Aortic Valve Implantation (TAVI) outcomes. TAVR offers helpful therapeutic choices to individuals who would not have been considered for valve replacement, despite the fact that it is not risk-free. In terms of recuperation, the experience of a person with a TAVR operation can resemble that of a coronary angiography. The treatment of severe aortic stenosis (AS) has been transformed by transcatheter aortic valve implantation, yet, it is still unknown how sex difference affects TAVI results. Thereby, Manoj Kumar and his colleagues looked at how post-procedural outcomes of TAVI, such as readmission rates and healthcare burden, differed for men and women.

To find hospitalizations for TAVI, the Nationwide Readmissions Database (2016–2020) was utilized. Males and females were matched using a propensity score matching (PSM) algorithm. Pearson's chi-squared test was employed to analyze the results. A total of 1,42,054 (44.3%) of the 3,20,324 TAVI hospitalizations involved surgical procedures on the female patients.

In-hospital mortality, stroke, post-procedural hemorrhage, vascular complications, acute respiratory failure (ARF), pericardial complications, transfusion requirement, vasopressor need, and major adverse cardiac and cerebrovascular events (MACCE) were all greater among women after propensity matching.