Intravascular imaging-guided PCI tied to fewer complications than angiography-guided PCI
Joo Myung Lee, M.D., PhD, M.P.H in his study, said that in patients with a history of complex coronary-artery lesions, intravascular imaging-guided PCI is related to a lower risk of complications cardiac causes, target-vessel–related myocardial infarction, or clinically driven target-vessel revascularization than angiography-guided PCI.
Explaining the study background, they said there is a scarcity of data considering clinical outcomes after intravascular imaging–guided PCI for complex coronary-artery lesions compared to the outcomes after angiography-guided PCI.
To add more research and data to the aforementioned background, in this study, researchers assigned patients with complex coronary-artery lesions in a 2:1 ratio to undergo either intravascular imaging–guided PCI or angiography-guided PCI. The composite of death from cardiac causes, target-vessel–related myocardial infarction, or clinically driven target-vessel revascularization were the primary outcomes measured in the study.
The results of the study are:
- One thousand six hundred thirty-nine patients underwent randomization.
- The number of participants in intravascular imaging–guided PCI and angiography-guided PCI were 1092 and 547, respectively.
- At a median follow-up of 2.1 years, a primary end-point event occurred in 76 patients and 60 patients in the intravascular imaging and angiography groups, with a cumulative incidence of 7.7% and 12.3 %, respectively.
- In the intravascular imaging and angiography groups, 16 patients and 17 died due to cardiac causes, with a cumulative incidence of 1.7 % and 3.8 %, respectively.
- 30 and 38 patients had target-vessel–related myocardial infarction with a cumulative incidence of 3.7% and 5.6%, respectively.
- Thirty-two patients and 25 patients had clinically driven target-vessel revascularization with a cumulative incidence of 3.4% and 5.5% respectively.
- Researchers reported no apparent between-group differences in the incidence of procedure-related safety events.
Concluding further, they said among those with complex coronary-artery lesions, intravascular imaging–guided PCI has fewer complications like death due to cardiac causes, target-vessel–related myocardial infarction, or clinically driven target-vessel revascularization than angiography-guided PCI.
This research was supported by Abbott Vascular and Boston Scientific, as acknowledged.
Further reading:
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.