Kansas City questionnaire is more accurate for outcome prediction than NYHA class, JAMA study.
The New York Heart Association (NYHA) functional classification system has been a cornerstone nomenclature for quantifying the health status of patients with heart failure (HF) for almost a century, and remains foundational to eligibility criteria for contemporary HF trials and application of clinical guidelines. This clinician-reported classification system has some major limitations. In the March issue of JAMA Cardiology, Greene and colleagues have shown that the patient- vs clinician-reported outcome discrepancy extends to heart failure care and patient-reported Kansas City Cardiomyopathy Questionnaire Overall Summary Score (KCCQ-OS) is more accurate for outcome prediction in heart failure patients.
To characterize longitudinal changes and concordance between NYHA class and the KCCQ-OS, and their associations with clinical outcomes Greene et al included 2872 US outpatients with chronic HF with reduced ejection fraction across 145 practices enrolled in the CHAMP-HF registry. All patients had complete NYHA class and KCCQ-OS data at baseline and 12 months. Longitudinal changes and correlations between the 2 measure were examined.
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