Loop Diuretics in Heart Failure: Torsemide and furosemide equally effective regardless of HF type
Written By : Dr Riya Dave
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2023-11-18 03:45 GMT | Update On 2023-11-18 09:40 GMT
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A recent post hoc analysis of the TRANSFORM-HF trial explored the clinical profiles and outcomes of heart failure (HF) patients treated with torsemide versus furosemide, focusing on differences between de novo HF and worsening chronic HF (WHF). This study was published in JAMA Cardiology by Selim R. and colleagues.
The study included 2,858 patients with documented ejection fraction, revealing that 838 patients had de novo HF, and 2,020 had WHF. Noteworthy distinctions were observed, with de novo HF patients being younger, having a higher glomerular filtration rate, lower natriuretic peptide levels, and receiving lower doses of loop diuretics compared to WHF patients.
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