No Added Benefit of Immediate Angiography among individuals resuscitated from Cardiac Arrest Without ST-Elevation: JAMA
A new study published in the Journal of American Medical Association showed no advantage to immediate coronary angiography compared to a delayed or selective approach in patients successfully resuscitated from out-of-hospital cardiac arrest (OHCA) without ST-segment elevation. No patient subgroup showed a differing treatment response.
There was no difference in short-term survival between immediate and delayed coronary angiography in patients with out-of-hospital cardiac arrest (OHCA) who did not have ST-segment abnormalities, according to a number of randomized clinical trials (RCTs). It is yet unknown, though, how these tactics relate to long-term results and which patient subgroups could profit from customized treatment.
Thus, to determine the impact of immediate versus delayed or selective coronary angiography treatment strategies on 1-year survival for patients with OHCA without ST elevation, as well as to identify subgroups that may have different treatment outcomes depending on patient or clinical characteristics, this study was carried out.
From the beginning until September 8, 2022, Embase, Ovid MEDLINE, and Clarivate/Web of Science Core Collection were searched for pertinent material. RCTs with a minimum follow-up time of one year that examined immediate vs delayed or selective coronary angiography following OHCA without ST-segment elevations were included.
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