NTproBNP levels can predict future events in non-severe AS, JAMA study.
Written By : dr. Abhimanyu Uppal
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2022-02-23 03:30 GMT | Update On 2022-02-23 03:31 GMT
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Is non-severe aortic stenosis (AS) really as benign as we think? Recent studies have questioned the presumed low-risk status of patients with asymptomatic non-severe aortic stenosis (AS). This calls for a novel marker to risk stratify non-severe AS patients into those at high clinical risk and those at lower risk for disease progression.
In the recent issue of JAMA Cardiology, researchers Hadziselimovic et al have proposed a new risk marker for AS i.e. NT proBNP and have shown that NT-proBNP concentrations within the reference range at year 1 are associated with low clinical risk in patients with asymptomatic nonsevere AS. Conversely, an increased 1-year NT-proBNP level may be associated with high aortic valve events (AVE) rates.
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