Orbital atherectomy reasonable strategy for treatment of severely calcified ostial and non-ostial lesions

• Researchers identified 609 patients who underwent PCI with OA.
• The participants were 63 % males aged 74 years (mean age).
• 81.9 % of patients had non-ostial lesions.
• The ostial lesions were present in 16.6 % of patients, and 2.8 % were aorto-ostial.
• 1.5 % of patients had unknown lesion anatomy.
• All patients received drug-eluting stent (DES) placement, and the overall freedom from MACE was 98.5 %,
• There was no difference between the ostial and non-ostial groups.
• There were similarities between the groups about freedom from cardiac death and MI.
• Researchers recorded low rates of bleeding complications and severe angiographic complications.
• There was no persistent slow flow/no-reflow reported.

Concluding further, they said our study had limitations like limited generalizability and less experienced non-tertiary centres, analysis of only in-hospital data and no reflection of long-term outcomes of patients.

This study found that using Orbital atherectomy for both ostial and non-ostial coronary artery disease patients was related to favourable in-hospital freedom from major adverse cardiovascular events (MACE) rates, low bleeding rates, and severe angiographic complications.

Further reading:

https://www.sciencedirect.com/science/article/abs/pii/S1553838923007108