Plaques with fibrous cap thickness of < 65 um prone to rupture, OCT study reveals
CHINA: A study published in BMC Cardiovascular Disorders found that, plaques with a fibrous cap thickness of 65 to 80 μm were more likely to rupture and/or thrombose than those with a cap thickness of 80 μm or more.
Acute coronary syndrome (ACS), a key contributor to morbidity and mortality in people with coronary artery disease, is typically brought on by the rupture of coronary plaque (CAD). One of the significant developments in the fight against ACS is the early diagnosis of plaques that are prone to rupture, or susceptible plaques. Current Optical coherence tomography (OCT) based research contradicts findings from an earlier autopsy investigation.
Therefore, the authors of this study used OCT to further analyze the relationship between plaque rupture or thrombosis and 65 μm < FCT ≤ 80 μm.
OCT was used to identify FCT for this purpose on the culprit lesions in 502 consecutively recruited patients. According to FCT, patients were divided into three groups: Group A (FCT ≤ 65 m, n = 147), Group B (65 fct ≤ 80 m,="" n="84),"(fct="" 80 m, n = 271). The inpatient medical record system was used to gather clinical and laboratory data. The association between FCT and plaque rupture and/or thrombosis was examined using univariable and multivariable logistic regression models. fct ≤ 80
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.