Polymer-free stents no better than durable-polymer stents in long run
Germany: Polymer-free versus durable polymer drug-eluting stent (DES) yielded no measurable differences at 10 years in patients with coronary artery disease (CAD), show results from ISAR-TEST-5 trial. The study, published in the Journal of the American College of Cardiology, found the incidence of stent thrombosis to be low and comparable in both the groups. Also, long-term adverse outcomes were similar for both groups.
There is a limited outcome data after extended long-term follow-up of patients with coronary artery disease treated with drug-eluting stents (DES) in CAD patients treated with DES in randomized clinical trials. Stenting done with polymer-free or durable polymer DES may yield performance differences that may emerge over time. Sebastian Kufner, Deutsches Herzzentrum München, Technische Universität München, Munich, Germany, and colleagues assessed the 10-year outcomes of patients enrolled in the ISAR-TEST-5 (Test Efficacy of Sirolimus- and Probucol-Eluting Versus Zotarolimus-Eluting Stents) trial.
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