Quantitative CMR may independently Predict Adverse Outcomes in In patients with Prior CABG
Patients with previous coronary artery bypass graft (CABG) surgery typically have complex coronary disease and remain at high risk of adverse events. A recent study suggests that in patients with prior CABG, myocardial blood flow (MBF) and perfusion reserve (MPR) derived from perfusion mapping cardiac magnetic resonance (CMR) identify high-risk patients beyond clinical history alone. The study findings were published in the Journal of The American College of Cardiology on March 21, 2022.
Quantitative myocardial perfusion indices predict outcomes in native vessel disease, but their prognostic performance in patients with prior CABG is unknown. Therefore, Dr Andreas Seraphim and his team conducted a study to evaluate whether global stress MBF and MRF derived from perfusion mapping CMR independently predict adverse outcomes in patients with prior CABG.
It was a retrospective analysis of 341 patients with prior CABG referred for adenosine stress perfusion CMR. The researchers performed perfusion mapping in line with automated quantification of MBF. The major outcome assessed was a composite of all-cause mortality and major adverse cardiovascular events defined as nonfatal myocardial infarction and unplanned revascularization. They further evaluated the associations with the use of Cox proportional hazards models after adjusting for comorbidities and CMR parameters.
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.