Radial wall strain novel measure of plaque composition and vulnerability in coronary stenosis patients: Study
China: A recent study has shown that angiography-derived radial wall strain (RWS) significantly corresponds with plaque composition and vulnerability in patients with intermediate coronary stenosis. The study appeared in the journal EuroIntervention.
The thin-cap fibroatheroma (TCFA) and the lipid-to-cap ratio (LCR) derived from optical coherence tomography indicate plaque vulnerability. Huihong Hong from Fujian Medical University Union Hospital in Fuzhou, China, and colleagues aimed to explore the association of a novel method for estimating RWS from angiography with features of plaque vulnerability assessed by OCT and plaque composition.
For this purpose, the researchers analyzed anonymized data from patients with intermediate stenosis who underwent CAG (coronary angiography) and OCT in a core laboratory. The TCFA and LCR were determined automatically on OCT images by an algorithm recently validated based on artificial intelligence. The angiography-derived RWSmax was computed as the lumen diameter's maximum deformation throughout the cardiac cycle, determined as a percentage of the largest lumen diameter.
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