Routine invasive therapy does not reduce major ischemic events: ISCHEMIA Trial
Ischemia is a serious concern as some part of the body, vital organs such as heart or brain, isn't getting enough blood. Approximately 1.5 million cases of ischemic myocardial infarction (MI) occur annually in the United States; the yearly incidence rate is approximately 600 cases per 100,000 people. The goal of myocardial ischemia treatment is to improve blood flow to the heart muscle. Depending on the severity of your condition, doctor may recommend medications, surgery or both.
The ISCHEMIA trial fails at proving that routine invasive therapy was associated with a reduction in major adverse ischemic events compared with optimal medical therapy among stable patients with moderate ischemia.
Trial is published in journal American College of Cardiology
The trial compared routine invasive therapy with optimal medical therapy among patients with stable ischemic heart disease and moderate to severe myocardial ischemia on noninvasive stress testing. Patients with stable ischemic heart disease and moderate to severe ischemia were randomized to routine invasive therapy included 2,588 participants versus medical therapy had 2,591.
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