Sacubitril/Valsartan combo effectively Manages Hypertension without affecting control in Diabetes Patients
Written By : Dr Prem Agarwal
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2023-11-04 04:30 GMT | Update On 2023-11-04 13:55 GMT
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In a study published in Cardiovascular Drugs and Therapy, sacubitril/valsartan, known for its favorable effects on blood pressure, has shown potential in managing hypertension among individuals with diabetes mellitus (DM). This research also explored the impact of sacubitril/valsartan on glycolipid metabolism.
This study was carried out to assess the antihypertensive effects of sacubitril/valsartan in patients with DM and primary hypertension. The primary objective was to measure the reduction in mean systolic blood pressure (SBP) with sacubitril/valsartan versus olmesartan after 8 weeks. Secondary endpoints included changes in diastolic blood pressure (DBP), daytime and nighttime SBP/DBP, blood pressure achievement, and lipid profile.
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