Sleep apnea and obesity may together cause severe impairment of cardiac function
Nearly 1 billion adults aged around 30-69 years worldwide were estimated to have obstructive sleep apnoea, with and without symptoms, based on an apnoea-hypopnoea index. Both obstructive sleep apnea (OSA)and obesity is said to cause myocardial remodeling and cardiac insufficiency via corresponding pathophysiological pathways. Therefore, it is speculated that the superposition of OSA and obesity may cause more severe impairment of cardiac function.
A recent study in The International journal of Cardiovascular Imaging reports that OSA patients,had myocardial strain was impaired before the damages in left ventricular ejection fraction, suggesting that the left ventricular systolic function is damaged early. The coexistence of obesity and OSA can lead to severe impairment of cardiac function through hypoxia and insulin resistance.
The objective of the study was to evaluate the early changes of left ventricular systolic function in obese patients with OSA with three-dimensional speckle tracking echocardiography(3D-STE).
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