Study finds monotonic relationship between systolic blood pressure and risk of CV outcomes in diabetes patients
Written By : Medha Baranwal
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2023-01-24 05:00 GMT | Update On 2023-01-24 09:42 GMT
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UK: In a recent study published in the journal Hypertension, researchers from the UK, using deep learning modeling, have found a monotonic relationship between systolic blood pressure (SBP) and the risk of cardiovascular (CV) outcomes in diabetes patients without evidence of a J-shaped relationship.
There is a controversy on whether the association between systolic blood pressure and cardiovascular disease (CVD) risk is monotonic or whether there is a nadir of optimal blood pressure. Kazem Rahimi from the University of Oxford in Oxford, UK, and colleagues investigated the association between systolic blood pressure and CV events in diabetes patients across the full spectrum of SBP.
For this purpose, the researchers identified a cohort of 49 000 patients with diabetes aged 50 to 90 years from linked electronic health records in the UK. A deep learning approach was used to analyze the associations between systolic blood pressure and cardiovascular outcomes (heart failure, ischemic heart disease, cardiovascular death, and stroke).
The authors reported the following findings:
· The authors observed 16 378 cardiovascular events over a median follow-up of 7.3 years.
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