Uninterrupted Oral Anticoagulant Therapy beneficial in patients undergoing PCI: JACC
In a recent research report, it has been highlighted that Interrupted Oral Anticoagulant ( I-OAC) and Uninterrupted Oral Anticoagulant Therapy (U-OAC) have equivalent risk for major adverse cardiac and cerebrovascular events and bleeding complications. Rather, it was noted that an U-OAC strategy was associated with shorter length of hospitalization. These data further support U-OAC as the preferable strategy in patients on OAC undergoing coronary intervention. Findings have been published in Journal of the American College of Cardiology.
There is a paucity of data regarding the optimal peri-procedural management of OAC-treated patients. So, this recent study sought to compare interrupted and uninterrupted oral anticoagulant therapy (I-OAC vs. U-OAC) in patients on OAC undergoing percutaneous coronary intervention.
For the study design,in the SWEDEHEART registry, all patients on OAC who were admitted acutely and underwent percutaneous coronary intervention or coronary angiography with a diagnostic procedure, from 2005 to 2017, were included. Outcomes were major adverse cardiac and cerebrovascular events (MACCE; death, myocardial infarction, or stroke) and bleeds at 120 days. Propensity score was used to adjust for the nonrandomized treatment selection.
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