Despite complete recovery, Sepsis induced cardiomyopathy has long-term adverse effects
A new study published in Annals of Intensive Care suggests that sepsis-induced cardiomyopathy (SIC) may continue to have an impact on the host's system even after recovery from cardiomyopathy due to greater in-hospital mortality in patients who were hospitalized for more than 10 days and 1-month mortality.
A life-threatening organ dysfunction, such as that of the respiratory, digestive, renal, immunological, neurological, and cardiovascular systems, results from a dysregulated immune response brought on by an infection. It is debatable whether sepsis-induced cardiomyopathy affects prognosis and how it relates to death at various stages. In order to comprehend the relationship between SIC and mortality in septic patients, Yu-Min Lin and colleagues carried out a comprehensive review and meta-analysis.
From the beginning until 8 July 2021, this team identified and evaluated observational data in PubMed and Embase addressing the mortality associated with SIC among septic patients. In-hospital and one-month mortality were the outcomes. To assess the mortality risk ratio in patients with and without SIC, the random-effects model was chosen. To investigate the outcome's heterogeneity, meta-regression, subgroup, and sensitivity analyses were used.
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