Rare case report of cyclosporine induced gingival hyperplasia
Suman Sethi and colleagues from the Department of Nephrology Dayanand Medical College and Hospital, Ludhiana, Punjab have recently studied an unusual case of cyclosporine induced gingival hyperplasia.
The study is published in the Journal of the Association of Physicians of India.
Drug-induced gingival overgrowth or enlargement manifests as abnormal growth of the gingiva due to an adverse drug reaction (ADR) in patients treated with anticonvulsants, immunosuppressants, and calcium channel blockers. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. It gradually becomes a source of pain and the condition often leads to disfiguration.
Researchers studied the case of a 28 year old male patient who was a known case of end stage renal disease on maintenance haemodialysis for last 1 year underwent live related renal transplant. The patient was on triple immunosuppression drugs (cyclosporine, MMF and glucocorticoids) for last 5 years and doing well on cyclosporine 75 mg twice daily, as the authors reported in their case report.
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