Direct Silver diamine fluoride application may cause pulp necrosis, reveals study

Written By :  Dr. Shravani Dali
Medically Reviewed By :  Dr. Kamal Kant Kohli
Published On 2022-03-19 03:30 GMT   |   Update On 2022-03-19 03:30 GMT

Direct Silver diamine fluoride (SDF) application causes pulp necrosis, according to a recent study published in the Journal of Dentistry. This study aims to review systematically the dental pulp response to silver diamine fluoride (SDF) treatment, including the inflammatory response, pulp cells activity, dentinogenesis, silver penetration, and the presence of the bacteria in the...

Login or Register to read the full article

Direct Silver diamine fluoride (SDF) application causes pulp necrosis, according to a recent study published in the Journal of Dentistry.

This study aims to review systematically the dental pulp response to silver diamine fluoride (SDF) treatment, including the inflammatory response, pulp cells activity, dentinogenesis, silver penetration, and the presence of the bacteria in the dental pulp.

In vitro studies, animal studies, clinical studies, and case reports on the use of SDF on vital dental pulp were included. Quality assessment of the included studies was conducted. A narrative synthesis of the collected data was performed.

A systematic search was performed in ProQuest, PubMed, SCOPUS, and Web of Science databases for articles published from inception to Nov 1, 2021.

The initial search identified 1,433 publications, of which five publications met the inclusion criteria. These five publications reported the effect of direct/ indirect SDF application on the vital pulp of a total of 30 teeth. Direct SDF application on vital pulp caused pulp necrosis. Indirect SDF application caused none or mild inflammatory response of dental pulp. The odontoblasts in the dental pulp showed increased cellular activity. Tertiary dentine was formed in the pulpal side of the cavity with indirect SDF application. Accentuated incremental lines of tertiary dentine reflected disturbances in mineralisation. Silver ions were found to penetrate along the dentinal tubules but were not detected inside the pulp.

Thus, according to the limited available literature, direct SDF application causes pulp necrosis. Indirect SDF application is generally biocompatible to dental pulp tissue with a mild inflammatory response, increased odontoblastic activity, and increased tertiary dentine formation. Future studies with precise quantitative and qualitative tests, a larger sample size and a longer follow-up time are imperative to understand the biological activity of dental pulp to SDF treatment.

Reference:

Effect of silver diamine fluoride on vital dental pulp: A systematic review by Ahmed Zaeneldin et al. published in the Journal of Dentistry.

https://www.sciencedirect.com/science/article/pii/S0300571222001233

Keywords:

silver diamine fluoride, vital dental pulp and silver diamine fluoride, silver diamine fluoride uses, silver diamine fluoride dental effect, Ahmed Zaeneldin Ollie Y., Yu Chun-HungChu, Journal of Dentistry, Silver diamine fluoride, dental pulp, direct pulp capping, indirect pulp capping, pulpal response


Tags:    
Article Source : Journal of Dentistry

Disclaimer: This site is primarily intended for healthcare professionals. Any content/information on this website does not replace the advice of medical and/or health professionals and should not be construed as medical/diagnostic advice/endorsement/treatment or prescription. Use of this site is subject to our terms of use, privacy policy, advertisement policy. © 2024 Minerva Medical Treatment Pvt Ltd

Our comments section is governed by our Comments Policy . By posting comments at Medical Dialogues you automatically agree with our Comments Policy , Terms And Conditions and Privacy Policy .

Similar News