Calcium hydroxide combined with chitosan nanoparticle most effective against Enterococcus faecalis

Each study used 24 samples of eight teeth each and was randomly divided into three groups based on the vehicle of calcium hydroxide: group 1: glycerin, group 2: CHX, and group 3: chitosan nanoparticles. Each vehicle group was then further divided into two subgroups of four teeth based on the interval times (group A: 7 days and group B: 14 days). The antibacterial efficacy was determined using an agar diffusion method. Calcium ion release was analyzed with atomic absorption spectrometry, and pH was measured using a pH meter. Statistical Analysis Used: Data from each study were analyzed by two-way ANOVA, followed by Tukey's test with a significance level of 95%.

Results:

The results exhibited that chitosan nanoparticles had the highest antibacterial efficacy against E. faecalis, calcium ion release, and pH, while the lowest was glycerin at 7 and 14 days (P < 0.05).

Thus, calcium hydroxide combined with chitosan nanoparticle as an intracanal medicament produced the highest antibacterial efficacy against E. faecalis, calcium ion release, and pH than glycerin and CHX at intervals of 7 and 14 days.

Reference:

Diatri Nari Ratih, Ema Mulyawati, Henytaria Fajrianti. Antibacterial efficacy, calcium ion release, and pH using calcium hydroxide with three vehicles. DOI: 10.4103/jcd.jcd_242_22

Keywords:

Antibacterial efficacy, calcium ion release, pH, calcium, hydroxide, three, vehicles, journal of conservative dentistry, Diatri Nari Ratih, Ema Mulyawati, Henytaria Fajrianti