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CPP-ACP containing varnish an effective remineralizing agent for white spot lesions

Written By :  Dr. Nandita Mohan
Medically Reviewed By :  Dr. Kamal Kant Kohli
Published On 2022-01-28 03:30 GMT   |   Update On 2022-01-28 03:30 GMT
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According to recent research, it has been found out that CPP-ACP containing varnish had higher remineralizing effect when compared to tricalcium phosphate (TCP) containing varnish on white spot lesions.

The study is published in the Open Access Macedonian Journal of Medical Sciences.
Casein phosphopeptides-amorphous calcium phosphate (CPP-ACP) is a bioactive agent with a base of milk products, which has been formulated from two parts: casein phosphopeptides (CPP) and amorphous calcium phosphate (ACP).
Ebaa Alagha and Amira Mohammad Samy from the Department of Restorative Dentistry, Al-Farabi Private Colleges, Jeddah, Saudi Arabia and School of Oral and Dental Medicine, Badr University, Badr City, Egypt carried out this study to evaluate the impact of two remineralizing agents containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and tricalcium phosphate (TCP) on white spot lesions.
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A total of 90 freshly extracted upper premolars were divided in three equal groups (30 each): Group A: Control group, Group B: Varnish containing CPP-ACP, and Group C: Varnish containing TCP. The teeth were subjected to Diagnodent test after inducing white spot lesions to assess any surface changes present on the teeth. The readings were repeated post-demineralization and post-remineralization.
The results showed that-
a. Statistically significant difference was present in the mean values between the tested groups.
b. CPP-ACP group recorded higher mean value at demineralization when compared to TCP group.
c. Statistically significant difference (p < 0.00`01) was present between the baseline and the demineralization values.
d. CPP-ACP group presented higher remineralization results when compared to TCP group.
e. T-test proved a significant difference between the tested groups.
Hence, it was concluded that "CPP-ACP containing varnish had higher remineralizing effect when compared to TCP containing varnish when treating white spot lesions."
Recently, the focus of restorative dentistry has been directed toward a conservative approach. Prevention and non-restorative treatment of initial enamel caries is the main concern. Remineralization procedures are the most preferred way of regeneration of lost tooth structure, the authors further added.


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Article Source : Open Access Macedonian Journal of Medical Sciences

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Dr. Nandita Mohan

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

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