Dexmedetomidine and midazolam equally effective sedative agents for third molar surgery
A recent study explored the efficacy of two common sedative agents, midazolam and dexmedetomidine, in third molar surgery-a prevalent minor oral surgical procedure in dentistry. The study findings suggest that both dexmedetomidine and midazolam are effective sedative agents for third molar surgery. This study was published in the journal Cureus by Alden Jason and colleagues.
The aim of the study was to evaluate their effectiveness and potential advantages in managing sedation during these procedures.
Sixty young adult patients, aged 18 to 50 years, without comorbidities, participated in the study. These individuals underwent third molar surgery, and their responses to sedation were observed and compared using the Observer’s Assessment of Alertness/Sedation scale. Patients were randomly assigned to receive either midazolam or dexmedetomidine. The effects of these sedatives on intraoperative vitals and sedation levels were assessed at 15-minute intervals.
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