Diabetic Nephropathy patients with Chronic Periodontitis tied to Increased Dyslipidemia risk

There is a 2.355-fold risk of developing Dyslipidemia in Type 2 Diabetic Nephropathy patients with Chronic Periodontitis as per a recent study that was published in the journal, "Journal of Periodontal Research, 2022." 

Periodontitis is a multifactorial inflammatory disease. It is the sixth complication of diabetes and can also affect other complications of diabetes, including nephropathy and coronary artery diseases. Some of the research done earlier considers Dyslipidemia as a risk factor for the exacerbation of periodontitis. So, Researchers from China investigated through a study, the association between periodontitis and total serum cholesterol level in patients with type 2 diabetic nephropathy (T2DN). 

An Observational study was carried out on 119 T2DN patients with chronic periodontitis. Patients were divided into two groups, the normal group having serum total cholesterol <5.17 mmol/L (n = 89) and the Dyslipidemia group with serum total cholesterol ≥5.17 mmol/L, (n = 30). All the participants finished a validated questionnaire that collected information on oral hygiene behaviors and knowledge of oral health, and also underwent a clinical oral examination. The number of teeth remaining, probing depth (PD), clinical attachment level (CAL), and bleeding index (BI) was recorded. Physical examination and certain laboratory tests like fasting plasma glucose, serum glycosylated hemoglobin (HbA1c), total cholesterol, high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), triglyceride, and high-sensitivity C-reactive protein levels were performed.