This double-blind, parallel randomized trial evaluated 140 mature permanent teeth in patients exhibiting either no symptoms or symptoms consistent with reversible pulpitis. The participants were randomly assigned to receive either direct pulp capping (67 teeth) or partial pulpotomy (73 teeth). All procedures were performed under magnification, with careful intraoperative hemostasis, and the same bioactive material (NeoPUTTY MTA) was used as the pulp capping agent.
Follow-up assessments were scheduled at 6 and 12 months, with both clinical and radiographic examinations performed to assess treatment success. Pre-treatment symptoms were present in roughly half of the cases (74 out of 140 teeth), with no statistical difference between the groups in terms of initial pain levels (p=0.75). Both treatment modalities resulted in significant pain reduction after one week (p<0.001), confirming short-term relief.
At the 6-month follow-up, failure was observed in 10 cases of direct pulp capping and 4 cases of partial pulpotomy. This translated to success rates of 94.4% for partial pulpotomy and 84.4% for direct pulp capping, a difference that approached but did not reach statistical significance (P=0.057).
At the 12-month mark, an additional two failures were reported in each group, yielding final success rates of 91.5% for partial pulpotomy and 81.3% for direct pulp capping. Again, while these findings suggested a trend favoring partial pulpotomy, the difference was not statistically significant (P=0.08).
Multivariate regression analysis revealed no significant prognostic indicators influencing treatment outcomes for either technique, which reinforced that both are viable options depending on case-specific clinical judgment.
The results suggest that partial pulpotomy may offer a marginally higher success rate in treating reversible pulpitis in cariously exposed mature permanent teeth. Both treatments showed excellent pain reduction and high success rates, but the slightly improved durability of partial pulpotomy may guide clinicians when choosing between the two, especially when pulp vitality is confirmed and bleeding is well-controlled.
Overall, the findings underline the importance of intraoperative evaluation and reinforce that, in the absence of firm guidelines, clinical discretion remains key in selecting the appropriate therapy.
Source:
Taha, N. A., Jaradat, H. B., DkmaK, A., & Abidin, I. Z. (2025). Carious pulp exposure in mature teeth with reversible pulpitis: a randomized clinical trial of direct pulp capping and partial pulpotomy. Journal of Endodontics. https://doi.org/10.1016/j.joen.2025.06.019
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.