Intravenous sedation useful for dental patients with severe dementia, finds Study

Medically Reviewed By : Dr. Kamal Kant Kohli

Published On 2021-02-04 23:30 GMT | Update On 2021-02-05 06:06 GMT

Researchers have recently found out that intravenous sedation for dental treatment in the elderly with severe dementia, needs a dose titration to about half the usual dose in Midazolam, as published in the Journal of Dental Sciences.

Patients with severe dementia require intravenous sedation during dental treatment. However, few reports have compared the outcomes of intravenous sedation management among sedatives. Intravenous sedation in the elderly with severe dementia undergoing dental treatment was evaluated retrospectively.

Therefore, Hitomi Nishizaki and colleagues from the Department of Critical Care Medicine and Dentistry, Graduate School of Dentistry, Kanagawa Dental University, Yokosuka, Japan conducted a retrospective cohort study of a Japanese population to analyze the effectiveness of intravenous sedation for dental treatment in elderly patients with severe dementia.

The authors obtained the patients' characteristics and type of dementia from medical records. Nineteen patients with severe dementia who underwent 62 instances of sedation were included. Midazolam (MID), dexmedetomidine (DEX), and propofol (PRO) were administered as sedatives. The systolic blood pressure (SBP), heart rate (HR), SpO2, bispectral index (BIS) values and complications were evaluated.

The following key findings were noted-

a. The sedation time and permission time to return home were significantly longer in DEX than in MID or PRO group.

b. Half the usual dose in MID and lower limits of the routine dose was effective in DEX and PRO.

c. HR was significantly lower in DEX group.

d. There were 3 cases with airway obstruction requiring nasopharyngeal airway and 4 cases of apnea when MID was administered.

e. Two cases of Cheyne-Stokes-like respiration when MID or DEX was administered.

f. SpO2 <94% was found in 22 cases (35%) irrespective of the sedative.

g. A patient with dementia with Lewy bodies had experienced hallucinations during the recovery period after sedation when MID or DEX was administered.

h. The BIS value of ≤80 was noted during complications.

Hence, it was concluded that "intravenous sedation for dental treatment in the elderly with severe dementia, needs a dose titration. All sedatives had respiratory-related complications which mandate close monitoring."

Article Source : Journal of Dental Sciences

Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.

NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.

Dr. Nandita Mohan

Dr. Nandita Mohan is a practicing pediatric dentist with more than 5 years of clinical work experience. Along with this, she is equally interested in keeping herself up to date about the latest developments in the field of medicine and dentistry which is the driving force for her to be in association with Medical Dialogues. She also has her name attached with many publications; both national and international. She has pursued her BDS from Rajiv Gandhi University of Health Sciences, Bangalore and later went to enter her dream specialty (MDS) in the Department of Pedodontics and Preventive Dentistry from Pt. B.D. Sharma University of Health Sciences. Through all the years of experience, her core interest in learning something new has never stopped. She can be contacted at editorial@medicaldialogues.in. Contact no. 011-43720751

Comments Policy

Our comments section is governed by our Comments Policy . By posting comments at Medical Dialogues you automatically agree with our Comments Policy , Terms And Conditions and Privacy Policy .

Intravenous sedation useful for dental patients with severe dementia, finds Study

Similar News

Fixed Orthodontic Treatment Linked to Increased Pulp Stone Formation: Study

Dental Council of India Invites Faculty Applications for Inspector Appointments

Diet Strongly Influences Enamel Hypoplasia Risk in Children: Study

Hemolaser Therapy Effectively Reduces Interdental Black Spaces and Improves Patient Comfort: Study

Flapless Immediate Implants with Bone Graft May Aid Bone Preservation, reveals research

Udaipur's Dental College BDS student commits suicide, alleges mental harassment in note, 2 accused faculty expelled

Hard evidence of soft teeth: the oral symptoms of hypophosphatasia

Delayed-Onset Peritonitis After Root Canal in PD Patient: Doctors Report First Case