Link Between Periodontitis and AMD: A Modifiable Risk Factor: Study

Results: Seven studies eligible for review included in total 149,217 individuals. Across the seven studies, different study designs, diagnoses and definitions of periodontitis, and diagnosis and definitions of AMD were employed. Our meta-analysis showed an association between periodontitis and AMD with an odds ratio of 1.42 (95% CI: 1.12 to 1.78; p = 0.003). Conclusions: Periodontitis is significantly associated with AMD. Unlike genetic predisposition and high age, which are important risk factors of AMD that cannot be modified, periodontitis is a risk factor that can be treated and potentially eliminated, thus allowing for a personalized approach for risk elimination in AMD. Attention should be given to the dental health of patients at risk of AMD.

Reference:

Boberg-Ans S, Arnold-Vangsted F, Scheel-Bech AB, Boberg-Ans LC, Arnold-Vangsted A, Jakobsen C, Stokbro K, Subhi Y. A Systematic Review and Meta-Analysis Association Between Periodontitis and Age-Related Macular Degeneration: Potential for Personalized Approach. J Pers Med. 2025 Apr 5;15(4):145. doi: 10.3390/jpm15040145. PMID: 40278325; PMCID: PMC12028726.