Microthreaded Collars Better Preserve Crestal Bone Despite Similar Inflammatory Response, claims research

Written By :  Dr. Shravani Dali
Published On 2026-01-15 14:30 GMT   |   Update On 2026-01-15 14:30 GMT
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Researchers have found in a new study that Both microthreaded versus Smooth implant collar designs showed limited impact on early peri-implant inflammation; however, microthreaded collars were more effective in preserving crestal bone.

A study was done to evaluate the impact of implant collar design on peri implant inflammatory biomarkers and crestal bone levels over a 6-month period. This pragmatic, randomized, parallel-group clinical trial was conducted at the Department of Prosthodontics and Crown and Bridge, Manav Rachna Dental College, between May 2023 and May 2024. The study included 30 systemically healthy patients aged 20–60 years with a single missing tooth in the mandibular molar region. Patients were randomly assigned to two groups based on the implant collar design – smooth or microthreaded. Implants were placed following a standardized two stage surgical protocol. Peri-implant crevicular fluid was collected at the time of implant placement, 3 months, and 6 months postplacement to assess inflammatory biomarkers (interleukin-1 [IL-1β] and tumor necrosis factor alpha [TNF-α]) using ELISA. Peri-implant crestal bone levels were measured radiographically at the same intervals. Statistical analysis was performed using the SPSS (version 21.0). The data were analyzed using appropriate statistical tests. P < 0.05 was considered statistically significant.

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Results: IL-1β and TNF-α increased in both groups at the 3-month follow-up, reflecting a typical postsurgical inflammatory response and subsequently decreased at 6 months. The changes in cytokine levels were not significantly different (P > 0.05) between groups, suggesting a similar inflammatory response regardless of collar design. Crestal bone levels in implants with microthreaded collar design exhibited significantly lower loss (0.44 mm) compared to smooth collar implants (0.94 mm), with a statistically significant mean difference of 0.5 mm (P = 0.019). Correlation analysis revealed no statistically significant relationships between crestal bone levels and inflammatory markers at any time point. 
Although both collar designs had a limited influence on the early peri-implant inflammatory response, but microthreaded collars were more effective in preserving crestal bone.

Reference:

Mishra, Paulina; Rani, Sapna; Dhawan, Pankaj; Goyal, Anjana1; Jain, Neha. Microthreaded versus smooth implant collars: A randomized trial on peri-implant inflammatory cytokines and crestal bone levels. The Journal of Indian Prosthodontic Society 26(1):p 87-95, Jan–Mar 2026. | DOI: 10.4103/jips.jips_453_25


Keywords:

Microthreaded, Collars, Better, Preserve, Crestal Bone, Despite, Similar, Inflammatory, Response, claims, research, Mishra, Paulina; Rani, Sapna; Dhawan, Pankaj; Goyal, Anjana1; Jain, Neha




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Article Source : The Journal of Indian Prosthodontic Society

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