Periodontal Treatment reduces Leptin, CRP and CVD risk in Obese patients: Study
Researchers have found out that nonsurgical periodontal treatment (NSPT) reduces serum levels of CRP and leptin while enhancing serum levels of adiponectin, in Thai patients with Owt or Ob, irrespective of periodontitis severity, as published in the International Journal of Dentistry.
Periodontitis and overweight or obesity independently change serum levels of leptin, adiponectin, and C-reactive protein (CRP).
Increased plasma levels of both leptin and CRP have been reported in a number of conditions, including obesity and inflammation, and have been linked to cardiovascular pathophysiological processes and increased cardiovascular risk.
Therefore, Notkamon Wanichkittikul and associates from the Department of Oral Medicine and Periodontology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand conducted this study to investigate the alterations of serum levels of leptin, adiponectin, and CRP after nonsurgical periodontal treatment (NSPT) in Thai patients with overweight or obesity (Owt/Ob) who did or did not exhibit severe periodontitis (SP) and normal weight (Nwt) patients with or without SP.
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