Pre-operative clindamycin may not reduce implant failure or complications after dental surgery
Oral implants are considered a predictable and safe treatment modality for the rehabilitation of missing teeth. However, there are reports on oral implant failure and one of main reasons for this is postoperative infections. The bacterial contamination of the implant bed during surgery are a significant cause of early implant failure, as well as being associated with late implant failure.
Pre-operative clindamycin administration during dental implant surgery in healthy adults may not reduce implant failure or post-surgical complications suggests a Prospective randomised placebo-controlled clinical trial.
The findings of the clinical trial have been published in the Evidence-Based Dentistry.
Clindamycin is a lincosamide type of antibiotic that's used to treat a variety of bacterial infections, including dental infection. It is usually given through oral route.
In the test group, the authors observed two implant failures and one patient experienced gastrointestinal disturbances and diarrhoea.
They also observed post-operative infections in three patients (two in the control group and one in the test group which eventually failed).
Subramani, K. Does pre-operative clindamycin administration during dental implant surgery reduce implant failure or post-surgical complications?. Evid Based Dent 23, 140–141 (2022). https://doi.org/10.1038/s41432-022-0838-6
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